biking?
First Avenue would be a likely route. It even has a connection to the Cherry Creek Trail via the ramp at Emerson St. Pearl Street would be a handy route from the south. Bannock Street south of 6th Avenue would be a likely connection to First Avenue. There is a traffic signal at First and Broadway to make for an easy crossing.
For additional bike paths, visit the City of Denver website.
riding the bus?
Here's one route: Go To: Champa St & 16th St (N Corner of Intersection), Denver
Get On: #1 / 1A Colorado Blvd 1A via Downtown at 9:42AM (Next Bus At 10:16AM)
Get Off: 1st Ave & Grant St (SE Corner of Intersection), Denver at 10:00AM (after 10:16 am, route is every half hour @ 16 & 46 minutes past the hour and traveler catches this route back into town on the opposite side of the street to return. Route is 1 or 1A on weedays/Saturdays, and just #1 on Sundays, running from downtown hourly @ 44 minutes past the hour (9:44, 10:44, etc.).
For additional bus routes, visit the RTD website.